ABSTRACT
Abstract Neonatal herpes is a serious condition. Newborns can be contaminated in utero via transplacental hematogenic transmission, upon delivery (the most frequent route), or during the postnatal period (indirect transmission). Optimal management requires prompt and accurate recognition, particularly in newborns, in order to prevent complications. Acyclovir is the treatment of choice, but its implementation is often delayed while awaiting test results, such as PCR and serology. Cytology for diagnostic purposes is rarely used in dermatology, despite the quick and reliable results. We report a case of neonatal herpes caused by type 2 herpes simplex virus diagnosed by cytology.
Subject(s)
Humans , Male , Infant, Newborn , Pregnancy Complications, Infectious/pathology , Herpesvirus 2, Human , Herpes Simplex/pathology , Antiviral Agents/therapeutic use , Pregnancy Complications, Infectious/drug therapy , Skin/pathology , Acyclovir/therapeutic use , Cytological Techniques , Herpes Simplex/drug therapyABSTRACT
Due to diverse clinical and histopathological presentations, diagnosis of secondary syphilis can occasionally prove challenging. Variable clinical presentations of secondary syphilis in HIV disease may result in an incorrect diagnosis and an inappropriate treatment regimen. Similarly, the histology of secondary syphilitic lesions may show considerable variation, depending on the clinical morphology of the eruption. We report a case of secondary syphilis in an HIV infected patient with cutaneous palmoplantar lesions simulating palmoplantar psoriasis.
.Subject(s)
Adult , Humans , Male , HIV Infections/pathology , Psoriasis/pathology , Syphilis, Cutaneous/pathology , Anti-Bacterial Agents/therapeutic use , Biopsy , Coinfection/drug therapy , Coinfection/pathology , Diagnosis, Differential , Keratoderma, Palmoplantar/drug therapy , Keratoderma, Palmoplantar/pathology , Penicillin G Benzathine/therapeutic use , Syphilis, Cutaneous/drug therapy , Treatment OutcomeABSTRACT
Stewart-Treves syndrome is a rare cutaneous angiosarcoma that develops in long-standing chronic lymphedema. Though most commonly this angiosarcoma is a result of post mastectomy lymphoedema, it also develops in Milroy disease, idiopathic, congenital, traumatic and filarial lymphoedema. Despite the rarity of this syndrome and its poor prognosis, early diagnosis associated with radical surgery can provide improved survival. We report a case of angiosarcoma in the lower limb in a patient with chronic lymphedema associated with history of repeated erysipela episodes.
.Subject(s)
Female , Humans , Middle Aged , Hemangiosarcoma/pathology , Lymphangiosarcoma/pathology , Lymphedema/pathology , Skin Neoplasms/pathology , Biopsy , Immunohistochemistry , Lower Extremity/pathologyABSTRACT
Metastasis is defined as a neoplastic lesion originating from another primary tumor, with which it is no longer in contact. Cutaneous metastases result from lymphatic embolization, hematogenous or contiguous dissemination or also direct implantation during surgical procedures. In women, the tumor most likely to metastasize to skin is breast cancer, which may manifest as papulonodular neoplastic lesions. We report the case of a 66 years old female patient, presenting papulonodular lesions13 years after the initial treatment with surgery and chemotherapy for a cancer of the left breast.
.Subject(s)
Aged , Female , Humans , Adenocarcinoma/secondary , Breast Neoplasms/pathology , Skin Neoplasms/secondary , Biopsy , Skin/pathology , Time FactorsABSTRACT
Lithium has been implicated in the exacerbation of pre-existing psoriasis, in the induction of psoriasis on previously uninvolved skin of psoriasis patients, and in the triggering of psoriasis for the first time in patients without a personal or family history. Lithium-induced psoriasis (and its resistance to treatment) is one of the major reasons for noncompliance in patients treated with lithium. We describe a male patient who developed generalized ostraceous psoriasis whose clinical appearance mimicked dermatitis neglecta, 10 months after starting therapy with lithium.
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